Focuses
2008
Focus on metals
Nature Chemical Biology Vol. 4, No. 3
In this issue, we highlight important recent advances in understanding both the chemistry and biology of metals in biological systems. We also feature new tools and approaches that can be used to gain a better understanding of the roles that metal ions play in cells and in whole organisms. We hope this collection of articles highlights the excitement of the 'chemical biology' of metals.
2007
Focus on molecular metrics
Nature Chemical Biology Vol. 3, No. 10
Cells and organisms have developed specialized systems to observe and respond to variables within their local environments. In this issue, we feature a collection of articles that focus on how biological systems measure space and time.
Focus on natural products
Nature Chemical Biology Vol. 3, No. 7
Investigations into natural products have recently regained prominence with the increasing understanding of their biological significance and increasing recognition of the origin and function of their structural diversity. This issue highlights some of the major questions and advances in natural products research, from recent synthetic approaches to access complicated natural products to a new educational program which utilizes natural products as a basis for discovery-based research.
Focus on RNA
Nature Chemical Biology Vol. 3, No. 1
RNA has occupied a pivotal position in the 'central dogma' of molecular biology, which states that information flows from DNA through RNA to proteins. In this issue, we feature a collection of articles that discuss the diverse functional roles of RNA in biological systems and highlight recent discoveries in RNA chemical biology, including advances in transcription, RNA structural biology, RNA interference and RNA engineering.
2006
Focus on drug discovery
Nature Chemical Biology Vol. 2, No. 12
The development of new therapeutic agents has required the close collaboration of chemists and biologists in identifying drug targets or lead compounds and developing them toward the clinic. This month we include a series of articles that focus on how chemical biologists in academic and industrial settings enhance our understanding of biological systems and advance the next generation of therapeutic agents.
1st anniversary highlights
Nature Chemical Biology Vol. 2, No. 6
The June 2006 issue represents one year of Nature Chemical Biology. To mark our anniversary, we have compiled some highlights from our first 12 issues. These free items reflect the editorial scope and the diversity of content featured in Nature Chemical Biology. We hope that you will enjoy them and look forward, with us, to our second year of publication of research at the interface of chemistry and biology.
