Focus on Heterogeneity

Messy biology and the origins of evolutionary innovations - pp692 - 696

Dan S Tawfik

doi:10.1038/nchembio.441

Biological messiness relates to infidelity, heterogeneity, stochastic noise and variation—both genetic and phenotypic—at all levels, from single proteins to organisms. Messiness comes from the complexity and evolutionary history of biological systems and from the high cost of accuracy. For better or for worse, messiness is inherent to biology. It also provides the raw material for physiological and evolutionary adaptations to new challenges.

Full Text - Messy biology and the origins of evolutionary innovations | PDF (230 KB) - Messy biology and the origins of evolutionary innovations

Focus on Heterogeneity

Judit Puskas - p697

Catherine Goodman

doi:10.1038/nchembio.449

A polymer scientist explores and exploits the heterogeneity of natural biopolymers.

Full Text - Judit Puskas | PDF (78 KB) - Judit Puskas

Focus on Heterogeneity

The role of physiological heterogeneity in microbial population behavior - pp705 - 712

Mary E Lidstrom & Michael C Konopka

doi:10.1038/nchembio.436

Abstract - The role of physiological heterogeneity in microbial population behavior | Full Text - The role of physiological heterogeneity in microbial population behavior | PDF (587 KB) - The role of physiological heterogeneity in microbial population behavior

Focus on Heterogeneity

A systematic approach to protein glycosylation analysis: a path through the maze - pp713 - 723

Karina Mariño, Jonathan Bones, Jayesh J Kattla & Pauline M Rudd

doi:10.1038/nchembio.437

Abstract - A systematic approach to protein glycosylation analysis: a path through the maze | Full Text - A systematic approach to protein glycosylation analysis: a path through the maze | PDF (1,003 KB) - A systematic approach to protein glycosylation analysis: a path through the maze

Focus on Heterogeneity

Heterogeneity in the chemistry, structure and function of plant cell walls - pp724 - 732

Rachel A Burton, Michael J Gidley & Geoffrey B Fincher

doi:10.1038/nchembio.439

Abstract - Heterogeneity in the chemistry, structure and function of plant cell walls | Full Text - Heterogeneity in the chemistry, structure and function of plant cell walls | PDF (1,059 KB) - Heterogeneity in the chemistry, structure and function of plant cell walls