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Nature Chemistry (23 January 2009) | doi:10.1038/nchem.117

Supramolecular chemistry: Another piece of the |[pi]|

Gavin Armstrong

Aromatic |[pi]|–|[pi]| interactions are important to many biological functions, including stabilizing the structure of DNA and in the binding of ligands to enzyme active sites. Although much of the previous work to understand the nature of such interactions has been directed towards benzene and substituted-benzene dimers, efforts are refocusing on identifying the effects of heteroatoms.