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Nature Chemistry 1, 527 - 528 (2009)
doi:10.1038/nchem.385

Subject Category: Analytical chemistry

Analytical chemistry: A dendritic signal amplifier

Magdalena A. Swiderska1 & Jean-Louis Reymond1

  1. Magdalena A. Swiderska and Jean-Louis Reymond are in the Department of Chemistry and Biochemistry, University of Berne, Freiestrasse 3, 3012 Berne, Switzerland.

Correspondence to: Jean-Louis Reymond1 e-mail: jean-louis.reymond@ioc.unibe.ch


Exponential signal amplification is achieved when a single molecule of analyte initiates a chain reaction in which a dendrimer releases a coloured 'reporter' molecule, and ultimately four further molecules of the analyte.

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