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Mass spectrometry

Tracking molecular mobility

By studying non-covalent assemblies in the gas phase, it is possible to examine the mobility of the components within a single complex — rather than between different complexes — using hydrogen/deuterium exchange reactions.

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Figure 1: Dynamics of a crown ether/oligolysine complex in the gas phase.

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Brodbelt, J. Tracking molecular mobility. Nature Chem 1, 526–527 (2009). https://doi.org/10.1038/nchem.382

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