The size and shape of amyloid-β protein assemblies have been studied using electrospray-ionization ion-mobility mass spectrometry, and the protein tetramers and dodecamers have been identified as an important oligomerization state in the development of neurodegenerative disease.
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Clemmer, D., Valentine, S. Protein oligomers frozen in time. Nature Chem 1, 257–258 (2009). https://doi.org/10.1038/nchem.264
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DOI: https://doi.org/10.1038/nchem.264
