Series
Series on Genomic Instability
Cells are exposed to both internal and external threats against the integrity of the genome. DNA damage and incorrect chromosome segregation can have deleterious effects such as cell death and uncontrolled proliferation. Therefore, multiple mechanisms are in place to ensure the surveillance and maintenance of genome integrity. Current topics in this exciting and active field have been discussed by leading scientists in a series of Reviews published in Nature Cell Biology over the past months. These are accompanied by a library of related research articles published recently in Nature Cell Biology and other Nature journals.
Editorial
Series on Genomic Instability
DOI: 10.1038/ncb2907; Nature Cell Biology 16, 1; (2014)
Reviews
Causes and consequences of replication stress
Michelle K Zeman and Karlene A Cimprich
DOI: 10.1038/ncb2897; Nature Cell Biology 16, 2–9; (2014)
Impact of genomic damage and ageing on stem cell function
Alex Behrens, Jan M van Deursen, K Lenhard Rudolph and Bjorn Schumacher
DOI: 10.1038/ncb2928; Nature Cell Biology 16, 201–207; (2014)
The biogenesis of chromosome translocations
Vassilis Roukos and Tom Misteli
DOI: 10.1038/ncb2941; Nature Cell Biology 16, 293–300; (2014)
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