Top 10

The top ten charts the articles that have been downloaded most often, in PDF format, from the Nature Cell Biology website in recent weeks. The chart does not rank the quality, scientific significance or citation impact of the content. However, it may bring articles to your attention that you might not have otherwise noticed. We hope you enjoy them.

1. News and Views

   MicroRNAs — keeping cells in formation

   Eric A. Miska

   doi:10.1038/ncb0508-501

   Full Text - MicroRNAs — keeping cells in formation | PDF (330 KB) - MicroRNAs — keeping cells in formation

2. Letter

   Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

   Khalid Al-Nedawi, Brian Meehan, Johann Micallef, Vladimir Lhotak, Linda May, Abhijit Guha & Janusz Rak

   doi:10.1038/ncb1725

   Abstract - Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells | Full Text - Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells | PDF (2,778 KB) - Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells | Supplementary information - Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

3. Letter

   p53 regulates glucose metabolism through an IKK-NF-B pathway and inhibits cell transformation

   Keiko Kawauchi, Keigo Araki, Kei Tobiume & Nobuyuki Tanaka

   doi:10.1038/ncb1724

   Abstract - p53 regulates glucose metabolism through an IKK-NF-B pathway and inhibits cell transformation | Full Text - p53 regulates glucose metabolism through an IKK-NF-B pathway and inhibits cell transformation | PDF (1,793 KB) - p53 regulates glucose metabolism through an IKK-NF-B pathway and inhibits cell transformation | Supplementary information - p53 regulates glucose metabolism through an IKK-NF-B pathway and inhibits cell transformation

4. Letter

   The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

   Philip A. Gregory, Andrew G. Bert, Emily L. Paterson, Simon C. Barry, Anna Tsykin, Gelareh Farshid, Mathew A. Vadas, Yeesim Khew-Goodall & Gregory J. Goodall

   doi:10.1038/ncb1722

   Abstract - The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 | Full Text - The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 | PDF (2,735 KB) - The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 | Supplementary information - The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

5. News and Views

   Starved cells eat ribosomes

   Hitoshi Nakatogawa & Yoshinori Ohsumi

   doi:10.1038/ncb0508-505

   Full Text - Starved cells eat ribosomes | PDF (597 KB) - Starved cells eat ribosomes

   See also: Letter by Kraft et al.

6. Letter

   Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation

   Clas B. Johansson, Sawsan Youssef, Kassie Koleckar, Colin Holbrook, Regis Doyonnas, Stephane Y. Corbel, Lawrence Steinman, Fabio M. V. Rossi & Helen M. Blau

   doi:10.1038/ncb1720

   Abstract - Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation | Full Text - Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation | PDF (2,261 KB) - Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation | Supplementary information - Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation

7. Letter

   Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease

   Claudine Kraft, Anna Deplazes, Marc Sohrmann & Matthias Peter

   doi:10.1038/ncb1723

   Abstract - Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease | Full Text - Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease | PDF (7,729 KB) - Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease | Supplementary information - Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease

8. Article

   Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell–cell and cell–matrix contacts

   Pipsa Saharinen, Lauri Eklund, Juho Miettinen, Riikka Wirkkala, Andrey Anisimov, Mark Winderlich, Astrid Nottebaum, Dietmar Vestweber, Urban Deutsch, Gou Young Koh, Bjorn R. Olsen & Kari Alitalo

   doi:10.1038/ncb1715

   Abstract - Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell–cell and cell–matrix contacts | Full Text - Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell–cell and cell–matrix contacts | PDF (16,338 KB) - Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell–cell and cell–matrix contacts | Supplementary information - Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell–cell and cell–matrix contacts

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