Perspective
Nature Cell Biology 9, 1010 - 1015 (2007)
doi:10.1038/ncb438
Convergent extension and the hexahedral cell
Jeremy B. A. Green1 & Lance A. Davidson2
Abstract
During development, embryonic cells sculpt three-dimensional tissues. Although cell polarity is commonly analysed along one, and sometimes two, dimensions, this perspective illustrates how higher-order cell polarity regulates convergent extension — the coordinated cell rearrangement that produces solid tissue elongation.
- Jeremy B. A. Green is in the Department of Craniofacial Development, King's College London, Guys Tower Floor 27, London SE1 9RT, UK.
- Lance A. Davidson is in the Department of Bioengineering, University of Pittsburgh, 3501 Fifth Avenue, 5059 Biomedical Sciences Tower 3, Pittsburgh 15260, PA, USA. e-mail: jeremy.green@kcl.ac.uk
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