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Nature Cell Biology 9, 1031 - 1034 (2007)
doi:10.1038/ncb0907-1031
Neural stem cells: guardians of the brain
Gianvito Martino1 & Stefano Pluchino1
- Gianvito Martino and Stefano Pluchino are in the Neuroimmunology Unit – DIBIT, and Institute of Experimental Neurology (InSpe), San Raffaele Scientific Institute, via Olgettina 58, I-20132, Milan, Italy. e-mail: martino.gianvito@hsr.it
Abstract
Toll-like receptors participate in the inflammatory response and are now shown to act in neural precursor cells to regulate adult hippocampal neurogenesis. The dialogue between inflammatory components and neural precursor cells might have important consequences for central nervous system homeostasis and repair.
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