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Nature Cell Biology 9, 880 - 881 (2007)
doi:10.1038/ncb0807-880

It takes guts to make a single lumen

Heinz-Georg Belting1 & Markus Affolter1

  1. Heinz-Georg Belting and Markus Affolter are in Growth and Development, Biozentrum der Universität Basel, Klingelbergstrasse 70, CH-4056 Basel, Switzerland e-mail: Markus.Affolter@unibas.ch


A new study of the zebrafish intestine has uncovered a transcriptional hierarchy controlling lumen formation and proposes a model for how transcellular and paracellular transport synergize to ensure that only a single lumen is produced.

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