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Nature Cell Biology 9, 736–738 (1 July 2007) | doi:10.1038/ncb0707-736

Centriole biogenesis: a tale of two pathways

Jadranka Loncarek , Greenfield Sluder & Alexey Khodjakov

The animal cell's primary microtubule-organizing centre, the centrosome, contains a pair of centrioles surrounded by pericentriolar material (PCM). As the number of centriole pairs determines the number of centrosomes the cell contains, the assembly of new centrioles must be under tight temporal and numerical control.