Table of contents


cover image
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Editorial

Free market science p721

doi:10.1038/ncb0707-721


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Book Review

Epigenetics for big and small p722

Asifa Akhtar reviews Epigenetics by C. David Allis, Thomas Jenuwein & Danny Reinberg

doi:10.1038/ncb0707-722


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Obituary

Charles Leblond 1910–2007 p723

Gary Bennett & John Bergeron

doi:10.1038/ncb0707-723


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Commentary

Irreversible cell-cycle transitions are due to systems-level feedback pp724 - 728

Bela Novak, John J. Tyson, Bela Gyorffy & Attila Csikasz-Nagy

doi:10.1038/ncb0707-724


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News and Views

MYC degradation: deubiquitinating enzymes enter the dance pp729 - 731

Bruno Amati & Victor J. Sanchez-Arévalo Lobo

doi:10.1038/ncb0707-729


p63: revving up epithelial stem-cell potential pp731 - 733

Cédric Blanpain & Elaine Fuchs

doi:10.1038/ncb0707-731


Threonine phosphorylation times bacterial secretion pp734 - 736

Hemantha D. Kulasekara & Samuel I. Miller

doi:10.1038/ncb0707-734


Centriole biogenesis: a tale of two pathways pp736 - 738

Jadranka Loncarek, Greenfield Sluder & Alexey Khodjakov

doi:10.1038/ncb0707-736


Extrinsic Wnt signalling controls the polarity component aPKC pp738 - 740

Shigeo Ohno

doi:10.1038/ncb0707-738


Autophagy: a new regulator of development p741

Nathalie Le Bot

doi:10.1038/ncb0707-741


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Articles

Dishevelled promotes axon differentiation by regulating atypical protein kinase C pp743 - 754

Xian Zhang, Ji Zhu, Guo-Ying Yang, Qing-Jie Wang, Lei Qian, Yan-Min Chen, Fei Chen, Yu Tao, Han-Song Hu, Tong Wang & Zhen-Ge Luo

doi:10.1038/ncb1603

See also: News and Views by Ohno


BACE1 regulates voltage-gated sodium channels and neuronal activity pp755 - 764

Doo Yeon Kim, Bryce W. Carey, Haibin Wang, Laura A. M. Ingano, Alexander M. Binshtok, Mary H. Wertz, Warren H. Pettingell, Ping He, Virginia M.-Y. Lee, Clifford J. Woolf & Dora M. Kovacs

doi:10.1038/ncb1602


The ubiquitin-specific protease USP28 is required for MYC stability pp765 - 774

Nikita Popov, Michael Wanzel, Mandy Madiredjo, Dong Zhang, Roderick Beijersbergen, Rene Bernards, Roland Moll, Stephen J. Elledge & Martin Eilers

doi:10.1038/ncb1601

See also: News and Views by Amati & Sanchez-Arévalo Lobo


MicroRNAs 17-5p–20a–106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation pp775 - 787

Laura Fontana, Elvira Pelosi, Paolo Greco, Serena Racanicchi, Ugo Testa, Francesca Liuzzi, Carlo M. Croce, Ercole Brunetti, Francesco Grignani & Cesare Peschle

doi:10.1038/ncb1613


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Letters

Molecular basis for the functional interaction of dynein light chain with the nuclear-pore complex pp788 - 796

Philipp Stelter, Ruth Kunze, Dirk Flemming, Dominic Höpfner, Meikel Diepholz, Peter Philippsen, Bettina Böttcher & Ed Hurt

doi:10.1038/ncb1604


Threonine phosphorylation post-translationally regulates protein secretion in Pseudomonas aeruginosa pp797 - 803

Joseph D. Mougous, Casey A. Gifford, Talia L. Ramsdell & John J. Mekalanos

doi:10.1038/ncb1605

See also: News and Views by Kulasekara & Miller


NUP98–NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis pp804 - 812

Gang G. Wang, Ling Cai, Martina P. Pasillas & Mark P. Kamps

doi:10.1038/ncb1608


Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility pp813 - 821

Hidekazu Iioka, Shun-ichiro Iemura, Tohru Natsume & Noriyuki Kinoshita

doi:10.1038/ncb1607


Maximal chromosome compaction occurs by axial shortening in anaphase and depends on Aurora kinase pp822 - 831

Felipe Mora-Bermúdez, Daniel Gerlich & Jan Ellenberg

doi:10.1038/ncb1606


Tension applied through the Dam1 complex promotes microtubule elongation providing a direct mechanism for length control in mitosis pp832 - 837

Andrew D. Franck, Andrew F. Powers, Daniel R. Gestaut, Tamir Gonen, Trisha N. Davis & Charles L. Asbury

doi:10.1038/ncb1609


Filamin-A regulates actin-dependent clustering of HIV receptors pp838 - 846

Sonia Jiménez-Baranda, Concepción Gómez-Moutón, Ana Rojas, Lorena Martínez-Prats, Emilia Mira, Rosa Ana Lacalle, Alfonso Valencia, Dimiter S. Dimitrov, Antonella Viola, Rafael Delgado, Carlos Martínez-A. & Santos Mañes

doi:10.1038/ncb1610


Wurst is essential for airway clearance and respiratory-tube size control pp847 - 853

Matthias Behr, Christian Wingen, Christian Wolf, Reinhard Schuh & Michael Hoch

doi:10.1038/ncb1611


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