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Letter

Nature Cell Biology 9, 813–821 (1 July 2007) | doi:10.1038/ncb1607

Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility

Hidekazu Iioka , Shun-ichiro Iemura , Tohru Natsume & Noriyuki Kinoshita

Gastrulation movements are critical for establishing the three germ layers and the architecture of vertebrate embryos. During Xenopus laevis gastrulation, mesodermal tissue migrates on the blastocoel roof and elongates along the antero-posterior axis.