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Letter
Nature Cell Biology 9, 822–831 (1 July 2007) | doi:10.1038/ncb1606
Maximal chromosome compaction occurs by axial shortening in anaphase and depends on Aurora kinase
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Abstract
Eukaryotic cells must first compact their chromosomes before faithfully segregating them during cell division. Failure to do so can lead to segregation defects with pathological consequences, such as aneuploidy and cancer.
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