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Letter

Nature Cell Biology 9, 788–796 (1 July 2007) | doi:10.1038/ncb1604

Molecular basis for the functional interaction of dynein light chain with the nuclear-pore complex

Philipp Stelter , Ruth Kunze , Dirk Flemming , Dominic H|[ouml]|pfner , Meikel Diepholz , Peter Philippsen , Bettina B|[ouml]|ttcher & Ed Hurt

Nucleocytoplasmic transport occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. Here, we discovered an unexpected role for yeast dynein light chain (Dyn2) in the NPC.