Table of contents


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Editorial

Biologistes sans frontières p613

doi:10.1038/ncb0607-613


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Book Review

Cell cycles explained p614

Christina Karlsson Rosenthal reviews The Cell Cycle: Principles of Control by David Morgan

doi:10.1038/ncb0607-614


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News and Views

PA promoted to manager pp615 - 617

John F. Hancock

doi:10.1038/ncb0607-615


Coding RNAs: separating the grain from the chaff pp617 - 619

Amin Ghabrial

doi:10.1038/ncb0607-617


Anchoring microtubules at the spindle poles pp619 - 621

Anne Paoletti & Phong T.

doi:10.1038/ncb0607-619


Caspase-14 and epidermis maturation pp621 - 622

Pierluigi Nicotera & Gerry Melino

doi:10.1038/ncb0607-621


Who, where, how many? p623

Sinéad Hayes

doi:10.1038/ncb0607-623


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Articles

Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells pp625 - 635

Shinji Masui, Yuhki Nakatake, Yayoi Toyooka, Daisuke Shimosato, Rika Yagi, Kazue Takahashi, Hitoshi Okochi, Akihiko Okuda, Ryo Matoba, Alexei A. Sharov, Minoru S. H. Ko & Hitoshi Niwa

doi:10.1038/ncb1589


STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels pp636 - 645

Joseph P. Yuan, Weizhong Zeng, Guo N. Huang, Paul F. Worley & Shmuel Muallem

doi:10.1038/ncb1590


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Letters

bold gamma-Tubulin complex-mediated anchoring of spindle microtubules to spindle-pole bodies requires Msd1 in fission yeast pp646 - 653

Mika Toya, Masamitsu Sato, Uta Haselmann, Kazuhide Asakawa, Damian Brunner, Claude Antony & Takashi Toda

doi:10.1038/ncb1593

See also: News and Views by Paoletti & T.


Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells pp654 - 659

Hadi Valadi, Karin Ekström, Apostolos Bossios, Margareta Sjöstrand, James J Lee & Jan O Lötvall

doi:10.1038/ncb1596


Small peptide regulators of actin-based cell morphogenesis encoded by a polycistronic mRNA pp660 - 665

Takefumi Kondo, Yoshiko Hashimoto, Kagayaki Kato, Sachi Inagaki, Shigeo Hayashi & Yuji Kageyama

doi:10.1038/ncb1595

See also: News and Views by Ghabrial


Caspase-14 protects against epidermal UVB photodamage and water loss pp666 - 674

Geertrui Denecker, Esther Hoste, Barbara Gilbert, Tino Hochepied, Petra Ovaere, Saskia Lippens, Caroline Van den Broecke, Petra Van Damme, Katharina D'Herde, Jean-Pierre Hachem, Gaetan Borgonie, Richard B. Presland, Luc Schoonjans, Claude Libert, Joël Vandekerckhove, Kris Gevaert, Peter Vandenabeele & Wim Declercq

doi:10.1038/ncb1597

See also: News and Views by Nicotera & Melino


Positional stability of single double-strand breaks in mammalian cells pp675 - 682

Evi Soutoglou, Jonas F. Dorn, Kundan Sengupta, Maria Jasin, Andre Nussenzweig, Thomas Ried, Gaudenz Danuser & Tom Misteli

doi:10.1038/ncb1591


Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair pp683 - 690

Elijahu Berkovich, Raymond J. Monnat, Jr. & Michael B. Kastan

doi:10.1038/ncb1599


Rad3-dependent phosphorylation of the checkpoint clamp regulates repair-pathway choice pp691 - 697

Mihoko Kai, Kanji Furuya, Francesca Paderi, Antony M. Carr & Teresa S.F. Wang

doi:10.1038/ncb1600


p73 supports cellular growth through c-Jun-dependent AP-1 transactivation pp698 - 706

Faina Vikhanskaya, Wen Hong Toh, Iqbal Dulloo, Qiang Wu, Lakshmanane Boominathan, Huck Hui Ng, Karen H. Vousden & Kanaga Sabapathy

doi:10.1038/ncb1598


Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos pp707 - 712

Chen Zhao, Guangwei Du, Karl Skowronek, Michael A. Frohman & Dafna Bar-Sagi

doi:10.1038/ncb1594

See also: News and Views by Hancock


The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2 pp713 - 719

Adam Mor, Gabriele Campi, Guangwei Du, Yang Zheng, David A. Foster, Michael L. Dustin & Mark R. Philips

doi:10.1038/ncb1592

See also: News and Views by Hancock


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