1. Anne Paoletti is in the Institut Curie, Centre de Recherche, Paris, F-75248, France and the CNRS, UMR 144, Paris, F-75248, France. e-mail: anne.paoletti@curie.fr
2. Phong T. Tran is at the University of Pennsylvania, Cell & Developmental Biology, 421 Curie Blvd Rm 1009, Philadelphia, PA 19104, USA. e-mail: tranp@mail.med.upenn.edu

Abstract

In the cell, microtubule organizing centers (MTOCs) dynamically nucleate microtubules and arrange them in functional patterns, but microtubule anchoring to MTOCs is not well understood. A novel fission-yeast protein that anchors the -tubulin-containing nucleating complex (-TuC) at the spindle pole during mitosis has now been described. The work highlights the complex regulation of microtubule anchoring.

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