Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Bridging efficient viral infection

Viral transmission from an infected cell to a target cell has been long appreciated to be more efficient than infection with a cell-free virus. New work using high-resolution, live-cell microscopy techniques provides important insights into the mechanisms underlying the efficiency of retrovirus transmission between cells.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Transfer of virus from infected cells to target cells along viral cytonemes.

References

  1. Igakura, T. et al. Science 299, 1713–1716 (2003).

    Article  CAS  Google Scholar 

  2. Johnson, D. C. & Huber, M. T. J. Virol. 76, 1–8 (2002).

    Article  CAS  Google Scholar 

  3. Sherer, N. M. et al. Traffic 4, 785–801 (2003).

    Article  CAS  Google Scholar 

  4. Lehmann, M. J., Sherer, N. M., Marks, C. B., Pypaert, M. & Mothes, W. J. Cell Biol. 170, 317–325 (2005).

    Article  CAS  Google Scholar 

  5. Sherer, N. M. et al. Nature Cell Biology 9, 255–267 (2007).

    Article  Google Scholar 

  6. Ramirez-Weber, F. A. & Kornberg, T. B. Cell 97, 599–607 (1999).

    Article  CAS  Google Scholar 

  7. McDonald, D. et al. Science 300, 1295–1297 (2003).

    Article  CAS  Google Scholar 

  8. Cavrois, M., Neidleman, J., Kreisberg, J. F. & Greene, W. C. PLoS Pathog 3, e4 (2007).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hope, T. Bridging efficient viral infection. Nat Cell Biol 9, 243–244 (2007). https://doi.org/10.1038/ncb0307-243

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncb0307-243

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing