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Nature Cell Biology 9, 133–134 (1 February 2007) | doi:10.1038/ncb0207-133

Tau is actin up in Alzheimer's disease

Gianluca Gallo

Alzheimer's patients present with a slow age-related neurodegeneration involving synaptic loss, axon and dendrite retraction, and the death of neurons. Previous work has identified the microtubule associated protein tau and β-amyloid (|[Agr]|β) peptides as potential mediators of Alzheimer's development.