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Letter
Nature Cell Biology 9, 201–209 (1 February 2007) | doi:10.1038/ncb1530
Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation
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Abstract
The transcription factor Gata-3 is a defining marker of the 'luminal' subtypes of breast cancer. To gain insight into the role of Gata-3 in breast epithelial development and oncogenesis, we have explored its normal function within the mammary gland by conditionally deleting Gata-3 at different stages of development.
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