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Nature Cell Biology 9, 135–136 (1 February 2007) | doi:10.1038/ncb0207-135

Luminal cells GATA have it

Thea D. Tlsty

“Cell differentiation is based almost certainly on the regulation of gene activity, so that for each state of differentiation a certain set of genes is active in transcription and other genes are inactive.” So wrote Roy Britten and Eric Davidson in their classic paper of 1969 speculating on the mechanistic basis of differentiation.