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From the following article

Chemotaxis in shallow gradients is mediated independently of PtdIns 3-kinase by biased choices between random protrusions

Natalie Andrew & Robert H Insall

Nature Cell Biology 9, 193 - 200 (2007) Published online: 14 January 2007

doi:10.1038/ncb1536

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Cells of different types generate new protrusions by subdividing existing ones.

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Figure 2

Rate of pseudopod production does not depend on orientation.

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Figure 3

Probability of survival of a pseudopod is biased by its position in a gradient.

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Figure 4

Cells chemotax by generating many pseudopods and retaining the better ones.

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Figure 5

Blocking PI(3)K alters the dynamics of pseudopod generation, but not the directional accuracy of the cell.

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