Celebrity cells - p1335

doi:10.1038/ncb1207-1335

Inspired by the visual spectacle cells offer under the microscope, some biologists have decided to put them on show.

Full Text - Celebrity cells | PDF (164 KB) - Celebrity cells

A not-so-rough guide to genes and cloning - p1336

Morag Stewart & Mickie Bhatia review The Rough Guide to Genes and Cloning by Jess Buxton & Jon Turney

doi:10.1038/ncb1207-1336

Full Text - A not-so-rough guide to genes and cloning | PDF (131 KB) - A not-so-rough guide to genes and cloning

Normal brain development in importin-5 deficient-mice - pp1337 - 1338

Tatjana Shmidt, Franziska Hampich, Michael Ridders, Stefanie Schultrich, Volkmar H. Hans, Katja Tenner, Larissa Vilianovich, Fatimunnisa Qadri, Natalia Alenina, Enno Hartmann, Matthias Köhler & Michael Bader

doi:10.1038/ncb1207-1337

Full Text - Normal brain development in importin-5 deficient-mice | PDF (424 KB) - Normal brain development in importin-5 deficient-mice

Reply to "Normal brain development in importin-5 deficient-mice" - p1339

Noriko Yasuhara & Yoshihiro Yoneda

doi:10.1038/ncb1207-1339

Full Text - Reply to "Normal brain development in importin-5 deficient-mice" | PDF (448 KB) - Reply to "Normal brain development in importin-5 deficient-mice"

Entosis: cell death by invasion - p1346

Nathalie Le Bot

doi:10.1038/ncb1207-1346

Full Text - Entosis: cell death by invasion | PDF (178 KB) - Entosis: cell death by invasion

Leading the charge - pp1341 - 1342

Derek C. Radisky

doi:10.1038/ncb1207-1341

Collective cell invasion into the extracellular matrix (ECM) has been observed in malignant tumours and in tissue morphogenesis. To achieve this, leading cells trigger both proteolytic and structural modifications of the ECM to create channels that precede progressively widening chains of following cells.

Full Text - Leading the charge | PDF (232 KB) - Leading the charge

Ring around the genes - pp1343 - 1344

Tanya M. Spektor & Judd C. Rice

doi:10.1038/ncb1207-1343

How is RNA Polymerase II (RNAP) regulated at poised loci in embryonic stem cells? Recent work provides new insights into Ring1-mediated transcriptional control of this important subset of developmental regulatory genes.

Full Text - Ring around the genes | PDF (189 KB) - Ring around the genes

Much HUBbub about stem-cell niches - pp1344 - 1345

Mark Van Doren

doi:10.1038/ncb1207-1344

Stem cells, and the microenvironment or 'niche' that influences them, must often reside in a particular location within a tissue to perform their function. Integrin-mediated adhesion is now shown to regulate the location of the stem-cell niche in the Drosophila testis.

Full Text - Much HUBbub about stem-cell niches | PDF (250 KB) - Much HUBbub about stem-cell niches

Corrigendum - p1442

doi:10.1038/ncb1207-1442a

Full Text - Corrigendum | PDF (78 KB) - Corrigendum

Addendum - p1442

doi:10.1038/ncb1207-1442b

Full Text - Addendum | PDF (83 KB) - Addendum

Filopodia are required for cortical neurite initiation - pp1347 - 1359

Erik W. Dent, Adam V. Kwiatkowski, Leslie M. Mebane, Ulrike Philippar, Melanie Barzik, Douglas A. Rubinson, Stephanie Gupton, J. Edward Van Veen, Craig Furman, Jiangyang Zhang, Arthur S. Alberts, Susumu Mori & Frank B. Gertler

doi:10.1038/ncb1654

Abstract - Filopodia are required for cortical neurite initiation | Full Text - Filopodia are required for cortical neurite initiation | PDF (10,788 KB) - Filopodia are required for cortical neurite initiation | Supplementary information

Filopodial actin bundles are not necessary for microtubule advance into the peripheral domain of Aplysia neuronal growth cones - pp1360 - 1369

Dylan T. Burnette, Andrew W. Schaefer, Lin Ji, Gaudenz Danuser & Paul Forscher

doi:10.1038/ncb1655

Abstract - Filopodial actin bundles are not necessary for microtubule advance into the peripheral domain of : Aplysia: neuronal growth cones | Full Text - Filopodial actin bundles are not necessary for microtubule advance into the peripheral domain of Aplysia neuronal growth cones | PDF (2,195 KB) - Filopodial actin bundles are not necessary for microtubule advance into the peripheral domain of Aplysia neuronal growth cones | Supplementary information

SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment - pp1370 - 1380

Colin J. Traer, Anna C. Rutherford, Krysten J. Palmer, Thomas Wassmer, Jacqueline Oakley, Naomi Attar, Jez G. Carlton, Joachim Kremerskothen, David J. Stephens & Peter J. Cullen

doi:10.1038/ncb1656

Abstract - SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment | Full Text - SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment | PDF (2,866 KB) - SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment | Supplementary information

Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts - pp1381 - 1391

Nagaraj Balasubramanian, David W. Scott, J. David Castle, James E. Casanova & Martin Alexander Schwartz

doi:10.1038/ncb1657

Abstract - Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts | Full Text - Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts | PDF (5,038 KB) - Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts | Supplementary information

Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells - pp1392 - 1400

Cedric Gaggioli, Steven Hooper, Cristina Hidalgo-Carcedo, Robert Grosse, John F. Marshall, Kevin Harrington & Erik Sahai

doi:10.1038/ncb1658

Abstract - Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells | Full Text - Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells | PDF (2,298 KB) - Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells | Supplementary information

See also: News and Views by Le Bot

Genome-scale RNAi profiling of cell division in human tissue culture cells - pp1401 - 1412

Ralf Kittler, Laurence Pelletier, Anne-Kristine Heninger, Mikolaj Slabicki, Mirko Theis, Lukasz Miroslaw, Ina Poser, Steffen Lawo, Hannes Grabner, Karol Kozak, Jan Wagner, Vineeth Surendranath, Constance Richter, Wayne Bowen, Aimee L. Jackson, Bianca Habermann, Anthony A. Hyman & Frank Buchholz

doi:10.1038/ncb1659

Abstract - Genome-scale RNAi profiling of cell division in human tissue culture cells | Full Text - Genome-scale RNAi profiling of cell division in human tissue culture cells | PDF (1,821 KB) - Genome-scale RNAi profiling of cell division in human tissue culture cells | Supplementary information

Integrin-dependent anchoring of a stem-cell niche - pp1413 - 1418

Guy Tanentzapf, Danelle Devenport, Dorothea Godt & Nicholas H. Brown

doi:10.1038/ncb1660

First Paragraph - Integrin-dependent anchoring of a stem-cell niche | Full Text - Integrin-dependent anchoring of a stem-cell niche | PDF (2,563 KB) - Integrin-dependent anchoring of a stem-cell niche | Supplementary information

See also: News and Views by Van Doren

MUC1 oncoprotein activates the IB kinase complex and constitutive NF-B signalling - pp1419 - 1427

Rehan Ahmad, Deepak Raina, Vishal Trivedi, Jian Ren, Hasan Rajabi, Surender Kharbanda & Donald Kufe

doi:10.1038/ncb1661

First Paragraph - MUC1 oncoprotein activates the I[kappa]B kinase [beta] complex and constitutive NF-[kappa]B signalling | Full Text - MUC1 oncoprotein activates the IB kinase complex and constitutive NF-B signalling | PDF (1,505 KB) - MUC1 oncoprotein activates the IB kinase complex and constitutive NF-B signalling | Supplementary information

Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells - pp1428 - 1435

Julie K. Stock, Sara Giadrossi, Miguel Casanova, Emily Brookes, Miguel Vidal, Haruhiko Koseki, Neil Brockdorff, Amanda G. Fisher & Ana Pombo

doi:10.1038/ncb1663

First Paragraph - Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells | Full Text - Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells | PDF (1,393 KB) - Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells | Supplementary information

Telomere lengthening early in development - pp1436 - 1441

Lin Liu, Susan M. Bailey, Maja Okuka, Purificación Muñoz, Chao Li, Lingjun Zhou, Chao Wu, Eva Czerwiec, Laurel Sandler, Andreas Seyfang, Maria A. Blasco & David L. Keefe

doi:10.1038/ncb1664

First Paragraph - Telomere lengthening early in development | Full Text - Telomere lengthening early in development | PDF (3,131 KB) - Telomere lengthening early in development | Supplementary information