1. Mark Van Doren is at the Department of Biology, 302 Mudd Hall, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA.
   e-mail: vandoren@jhu.edu

Abstract

Stem cells, and the microenvironment or 'niche' that influences them, must often reside in a particular location within a tissue to perform their function. Integrin-mediated adhesion is now shown to regulate the location of the stem-cell niche in the Drosophila testis.

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