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Letter
Nature Cell Biology 9, 1294–1302 (1 November 2007) | doi:10.1038/ncb1649
Coupling of cortical dynein and G|[alpha]| proteins mediates spindle positioning in Caenorhabditis elegans
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Abstract
Despite being essential for spatial cell division control, the mechanisms governing spindle positioning remain incompletely understood. In the Caenorhabditis elegans one-cell stage embryo, the spindle becomes asymmetrically positioned during anaphase through the action of as-yet unidentified cortical force generators that pull on astral microtubules and that depend on two Gα proteins and associated proteins.
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