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Nature Cell Biology 9, 1227–1229 (1 November 2007) | doi:10.1038/ncb1107-1227

HtrA2 and Parkinson's disease: think PINK?

Emad S. Alnemri

Exposure of cells to environmental or internal stress causes misfolding of or damage to many cellular proteins, and the ability of cells to respond to these stresses is paramount for survival. Cells have developed several mechanisms to detect, remove or correct misfolded or damaged proteins.