News and Views
Nature Cell Biology 9, 1225 - 1227 (2007)
doi:10.1038/ncb1107-1225
How size is controlled: from Hippos to Yorkies
Laura A. Buttitta1 & Bruce A. Edgar1
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Laura A. Buttitta and Bruce A. Edgar are at the Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
e-mail: bedgar@fhcrc.org
Abstract
How do developing organs sense and limit their size? The recently discovered Hippo pathway might have a critical role in controlling organ size and homeostasis in many organisms from Drosophila to mammals.
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