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Nature Cell Biology 9, 1221 - 1222 (2007)
doi:10.1038/ncb1107-1221
Holding back TOR advances mitosis
Thomas W. Sturgill1 & Michael N. Hall2
- Thomas W. Sturgill is at the Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.
-
Michael N. Hall is at the Biozentrum, University of Basel, Klingelbergstrasse 70, CH4056 Basel, Switzerland.
e-mail: m.hall@unibas.ch
Abstract
The control of cell size through the coordination of cell growth and division is a longstanding fundamental problem. A study in fission yeast shows that TOR controls entry into mitosis through the MAP kinase Sty1 and so provides a molecular mechanism for the control of cell size.
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