Table of contents


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Editorial

Opening up peer review p1

doi:10.1038/ncb0107-1


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Commentary

Defining an epigenetic code pp2 - 6

Bryan M. Turner

doi:10.1038/ncb0107-2


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Review

Lipid rafts: at a crossroad between cell biology and physics pp7 - 14

Ken Jacobson, Ole G. Mouritsen & Richard G. W. Anderson

doi:10.1038/ncb0107-7


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News and Views

Leading-edge research: PtdIns(3,4,5)P3 and directed migration pp15 - 17

Jonathan Franca-Koh, Yoichiro Kamimura & Peter N. Devreotes

doi:10.1038/ncb0107-15


Sculpting a fly leg: BMP boundaries and cell death pp17 - 18

Marco Milán

doi:10.1038/ncb0107-17


Heterochromatin: condense or excise pp19 - 20

Craig Pikaard & Olga Pontes

doi:10.1038/ncb0107-19


Wapl takes cohesin off chromosome arms p21

Nathalie Le Bot

doi:10.1038/ncb0107-21


Telomeres on the Cdk roller-coaster ride pp22 - 23

Miguel Godinho Ferreira

doi:10.1038/ncb0107-22


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Articles


Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1 pp36 - 44

Miki Nishio, Ken-ichi Watanabe, Junko Sasaki, Choji Taya, Shunsuke Takasuga, Ryota Iizuka, Tamas Balla, Masakazu Yamazaki, Hiroshi Watanabe, Reietsu Itoh, Shoko Kuroda, Yasuo Horie, Irmgard Förster, Tak W. Mak, Hiromichi Yonekawa, Josef M. Penninger, Yasunori Kanaho, Akira Suzuki & Takehiko Sasaki

doi:10.1038/ncb1515

See also: News and Views by Franca-Koh et al.


Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus pp45 - 56

Pavan Kumar P., Oliver Bischof, Prabhat Kumar Purbey, Dimple Notani, Henning Urlaub, Anne Dejean & Sanjeev Galande

doi:10.1038/ncb1516


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Letters

Sharp boundaries of Dpp signalling trigger local cell death required for Drosophila leg morphogenesis pp57 - 63

Cristina Manjón, Ernesto Sánchez-Herrero & Magali Suzanne

doi:10.1038/ncb1518

See also: News and Views by Milán


PGC7/Stella protects against DNA demethylation in early embryogenesis pp64 - 71

Toshinobu Nakamura, Yoshikazu Arai, Hiroki Umehara, Masaaki Masuhara, Tohru Kimura, Hisaaki Taniguchi, Toshihiro Sekimoto, Masahito Ikawa, Yoshihiro Yoneda, Masaru Okabe, Satoshi Tanaka, Kunio Shiota & Toru Nakano

doi:10.1038/ncb1519


Triggering neural differentiation of ES cells by subtype switching of importin-alpha pp72 - 79

Noriko Yasuhara, Noriko Shibazaki, Shinya Tanaka, Masahiro Nagai, Yasunao Kamikawa, Souichi Oe, Munehiro Asally, Yusuke Kamachi, Hisato Kondoh & Yoshihiro Yoneda

doi:10.1038/ncb1521


Regulation of protein tyrosine phosphatase 1B by sumoylation pp80 - 85

Shrikrishna Dadke, Sophie Cotteret, Shu-Chin Yip, Zahara M. Jaffer, Fawaz Haj, Alexey Ivanov, Frank Rauscher, III, Ke Shuai, Tony Ng, Benjamin G. Neel & Jonathan Chernoff

doi:10.1038/ncb1522


PI(3)Kbold gamma has an important context-dependent role in neutrophil chemokinesis pp86 - 91

G. John Ferguson, Laura Milne, Suhasini Kulkarni, Takehiko Sasaki, Simon Walker, Simon Andrews, Tom Crabbe, Peter Finan, Gareth Jones, Shaun Jackson, Montserrat Camps, Christian Rommel, Matthias Wymann, Emilio Hirsch, Phillip Hawkins & Len Stephens

doi:10.1038/ncb1517

See also: News and Views by Franca-Koh et al.


Basal-to-apical cadherin flow at cell junctions pp92 - 98

Yoshiko Kametani & Masatoshi Takeichi

doi:10.1038/ncb1520


Reducing mitochondrial fission results in increased life span and fitness of two fungal ageing models pp99 - 105

C.Q. Scheckhuber, N. Erjavec, A. Tinazli, A. Hamann, T. Nyström & H.D. Osiewacz

doi:10.1038/ncb1524


Cdk and APC activities limit the spindle-stabilizing function of Fin1 to anaphase pp106 - 112

Erika L. Woodbury & David O. Morgan

doi:10.1038/ncb1523


Dynein is required for receptor sorting and the morphogenesis of early endosomes pp113 - 120

Owen J. Driskell, Aleksandr Mironov, Victoria J. Allan & Philip G. Woodman

doi:10.1038/ncb1525


Shigella IpgB1 promotes bacterial entry through the ELMO–Dock180 machinery pp121 - 128

Yutaka Handa, Masato Suzuki, Kenji Ohya, Hiroki Iwai, Nozomi Ishijima, Anthony J. Koleske, Yoshinori Fukui & Chihiro Sasakawa

doi:10.1038/ncb1526


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