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Letter
Nature Cell Biology 9, 106–112 (1 January 2007) | doi:10.1038/ncb1523
Cdk and APC activities limit the spindle-stabilizing function of Fin1 to anaphase
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Abstract
The fidelity of chromosome segregation depends on proper regulation of mitotic spindle behaviour. In anaphase, spindle stability is promoted by the dephosphorylation of cyclin-dependent kinase (Cdk) substrates, which results from Cdk inactivation and phosphatase activation.
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