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Nature Cell Biology 9, 22–23 (1 January 2007) | doi:10.1038/ncb0107-22
Telomeres on the Cdk roller-coaster ride
Abstract
In recent years, the telomere field has been facing an interesting riddle: although telomerase purified from cell extracts is active throughout the cell cycle, telomeres are only extended in late S and G2 phases. Carol Greider and colleagues now provide evidence for the direct involvement of the cell-cycle master regulator Cdk1 (ref.
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