News and Views
Nature Cell Biology 9, 19 - 20 (2007)
doi:10.1038/ncb0107-19
Heterochromatin: condense or excise
- Craig Pikaard and Olga Pontes are in the Biology Department, Washington University, Campus Box 1137, One Brookings Drive, St Louis, MO 63130. USA. e-mail: pikaard@biology.wustl.edu
Abstract
In eukaryotes, condensing chromosomal DNA into heterochromatin is important for gene silencing and proper chromosome segregation. A recent study suggests a function for heterochromatin in protecting highly repeated genes and satellite DNA against excision caused by recombination or by joining of free DNA ends following DNA damage.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stabilityNature Cell Biology Article (01 Jan 2007)
Displacement of D1, HP1 and topoisomerase II from satellite heterochromatin by a specific polyamideThe EMBO Journal Article (07 Jun 2006)
Retrotransposon silencing and telomere integrity in somatic cells of Drosophila depends on the cytosine-5 methyltransferase DNMT2Nature Genetics Article (01 Jun 2009)
See all 10 matches for Research
