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Nature Cell Biology 8, 910–911 (1 September 2006) | doi:10.1038/ncb0906-910

Meiosis: separase strikes twice

Marie-Emilie Terret & Prasad V. Jallepalli

Ever since Walther Flemming first described the stages of mitosis in the late 19th century, cell biologists have been consumed with a desire to understand chromosome segregation in ever-increasing detail. In animal cells, the ring-like cohesin complex is maintained at sister centromeres until the start of anaphase.