Access

Letter

Nature Cell Biology 8, 978–985 (1 September 2006) | doi:10.1038/ncb1459

Sequential functioning of the ECT-2 RhoGEF, RHO-1 and CDC-42 establishes cell polarity in Caenorhabditis elegans embryos

Fumio Motegi & Asako Sugimoto

During development, the establishment of cell polarity is important for cells to undergo asymmetric cell divisions that give rise to diverse cell types. In C.