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Nature Cell Biology 8, 908–909 (1 September 2006) | doi:10.1038/ncb0906-908
CFTR: helping to acidify macrophage lysosomes
Abstract
Cystic fibrosis is a complex, heritable disease attributable to defects in a single protein, CFTR. Severe pathology results from chronic inflammation due to poor control of bacterial infections in the lungs.
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