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Nature Cell Biology 8, 790–791 (1 August 2006) | doi:10.1038/ncb0806-790
Balancing Mdm2 |[mdash]| a Daxx|[ndash]|HAUSP matter
Abstract
Marking proteins for degradation requires a well coordinated action of three enzymes in a sequential process. In the first step, the carboxy-terminal Gly residue of ubiquitin is activated by E1.
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