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Nature Cell Biology 8, 789 (1 August 2006) | doi:10.1038/ncb0806-789
Mesodermal Wnt expression promotes liver specification
Abstract
Endodermal organs, such as liver and lung, arise at specific locations along the primitive gut tube. Many of the signalling pathways that specify endodermal organs have been determined, but no single gene that exclusively regulates liver specification has been identified.
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