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Nature Cell Biology 8, 783–785 (1 August 2006) | doi:10.1038/ncb0806-783
Arp2/3 ATP hydrolysis: to branch or to debranch?
Abstract
The Arp2/3 complex is a pivotal regulator of actin-filament assembly for various cellular processes. In response to signalling triggers, the complex forms branched actin networks that provide the force for cellular locomotion, endocytosis, phagocytosis and intracellular transport of vesicles and bacterial pathogens.
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