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Nature Cell Biology 8, 650–651 (1 July 2006) | doi:10.1038/ncb0706-650

Actin's latest act: polymerizing to facilitate transcription?

Erwann Vieu & Nouria Hernandez

Various lines of evidence suggest that nuclear actin is required for efficient transcription by RNA polymerases (Pol) I, II and III. Nuclear actin seems to function in several steps of the transcription process, particularly during initiation complex assembly and transcription elongation.