Nature Cell Biology 8, 648 - 649 (2006)
doi:10.1038/ncb0706-648
Endosome sorting: GSE complex minds the GapMatthew N. J. Seaman
Matthew N. J. Seaman is in the University of Cambridge, Cambridge Institute for Medical Research and Department of Clinical Biochemistry, Addenbrookes Hospital, Hills Road, Cambridge, CB2 2XY. UK. mnjs100@cam.ac.uk
The general amino acids permease Gap1p provides yeast with sufficient amino acids to maintain protein synthesis. Gap1p is translocated to the plasma membrane when amino acids become limiting, a process that is mediated by a newly identified membrane complex called the GSE complex.
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