Nature Cell Biology 8, 645 - 647 (2006)
doi:10.1038/ncb0706-645
Unravelling mRNA exportCharles N. Cole1
& John J. Scarcelli21
Charles N. Cole is in the Departments of Biochemistry and Genetics, Dartmouth Medical School, Hanover, NH 03755, USA. charles.cole@dartmouth.edu
2
John J. Scarcelli is in the Department of Biochemistry, Dartmouth Medical School, Hanover, NH 03755, USA. john.scarcelli@dartmouth.edu
Precise spatial regulation of mRNA remodelling is crucial for proper gene expression. One way this is accomplished is through activation of the DEAD-box helicase Dbp5 at the cytoplasmic fibrils of the nuclear-pore complex, by the nucleoporin Gle1 and the soluble inositol polyphosphate InsP6.
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