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Letter
Nature Cell Biology 8, 631–639 (1 June 2006) | doi:10.1038/ncb1415
Roles of sumoylation of a reptin chromatin-remodelling complex in cancer metastasis
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Abstract
Defining the functional modules within transcriptional regulatory factors that govern switching between repression and activation events is a central issue in biology. Recently, we have reported the dynamic role of a β-catenin–reptin chromatin remodelling complex in regulating a metastasis suppressor gene KAI1 (ref.1), which is capable of inhibiting the progression of tumour metastasis.
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