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Letter

Nature Cell Biology 8, 586–593 (1 June 2006) | doi:10.1038/ncb1409

Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization

Yasushi Izumi , Nao Ohta , Kanako Hisata , Thomas Raabe & Fumio Matsuzaki

The orientation of the mitotic spindle relative to the cell axis determines whether polarized cells undergo symmetric or asymmetric divisions. Drosophila epithelial cells and neuroblasts provide an ideal pair of cells to study the regulatory mechanisms involved.