Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
News and Views
Nature Cell Biology 8, 1321–1323 (1 December 2006) | doi:10.1038/ncb1206-1321
S100 chemokines mediate bookmarking of premetastatic niches
&
Abstract
It has long been recognized that the preferential colonization of specific tissues by certain tumour types is, in part, determined by the unique nature of the microenvironment within distant target organs. Emerging evidence suggests that certain primary tumour cells release soluble factors that induce a specific population of non-malignant haematopoietic cells to mobilize and engraft distant organ tissues, thereby establishing a 'premetastatic niche' that lay a foundation for incoming circulating cancer cells.
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
