Figure 3 - From gene to protein to literature: a sample analysis.

Beginning with a gene sequence (top left), a protein sequence (below gene sequence) is generated and can be analysed with InterProScan to detect sequences indicative of the presence of known protein domains and families within the sequence, generating a graphical overview (top right). The sequence is also compared with known sequences in the UniProtKB database using the BLAST algorithm and the output displays an alignment (middle) between the query sequence and its best matches. The best match for the sample query data is the RAS1 protein from Saccharomyces cerevisiae. The corresponding UniProtKB entry features curated links for this protein to known publications (lower left). Additional publications for this protein, retrieved using text-mining methods, can be found by querying iHOP (lower right).