Review abstract
Nature Cell Biology 8, 1204 - 1211 (2006)
doi:10.1038/ncb1498
Modelling microtubule patterns
Eric Karsenti1, François Nédélec1 & Thomas Surrey1
Abstract
The cellular cytoskeleton is well studied in terms of its biological and physical properties, making it an attractive subject for systems approaches. Here, we describe the experimental and theoretical strategies used to study the collective behaviour of microtubules and motors. We illustrate how this led to the beginning of an understanding of dynamic cellular patterns that have precise functions.
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Eric Karsenti, François Nédélec and Thomas Surrey are in the European Molecular Systems Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.
e-mail: karsenti@embl.de; e-mail: nedelec@embl.de; e-mail: surrey@embl.de
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