Nature Cell Biology
- 8, 1215 - 1217 (2006)
doi:10.1038/ncb1106-1215
Ahead of the curve: mitochondrial fusion and phospholipase DRobert E. Jensen & Hiromi Sesaki
Robert E. Jensen and Hiromi Sesaki are in the Department of Cell Biology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. robjensen@jhmi.edu
A new study has identified a novel phospholipase D (PLD) that is located in the mitochondrial outer membrane and is required for organelle fusion. As PLD-catalysed production of fusogenic lipids is critical for many examples of membrane fusion (such as those mediated by SNAREs), this startling finding raises the possibility that mitochondria use a mechanism common to other cellular fusion events.
MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated.
|
