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Nature Cell Biology 8, 1050–1051 (1 October 2006) | doi:10.1038/ncb1006-1050

Kizuna takes pole position

Onur Cizmecioglu & Ingrid Hoffmann

To divide, cells need to duplicate and segregate their chromosomes accurately. The mitotic spindle is a cytoskeletal structure that mediates the equal distribution of the chromosomes into the two daughter cells and a key question in cell-cycle regulation is how a functional bipolar spindle assembles at the onset of mitosis to allow a faithful distribution of chromosomes.