1. Alexei Poliakov and David Wilkinson are in the Division of Developmental Neurobiology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK. e-mail: dwilkin@nimr.mrc.ac.uk

Abstract

Interactions between Eph receptors and ephrins can restrict or enable the movement of cells by promoting cell repulsion or invasion. Ephrins have now been shown to regulate cell migration by interacting with the planar cell polarity (PCP) pathway.

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